I am afraid that rejection and failure and disappointment are a regular feature of ordinary life, no matter how successful someone may be.
I hate rejection. In the past, I've been guilty of consciously avoiding situations where I might get rejected, both professionally and personally. I often steer clear of men who are “out of my league," and I've frequently held back from telling people my true feelings for fear they won't reciprocate. The last time a man turned me down I retorted (word-for-word, and I'm not proud of this): "You're either kidding yourself or you are just an arse." Ergh.
I'm working on
a) being comfortable with making myself vulnerable and
b) dealing with the inevitable occasional rejection in a dignified manner.
Resilience is learnable, but it takes practise.