settingsLogin | Registersettings
Show Menu

Oxidative Stress Induces Copper Acetate of Metal Thiocopper Bond

1 like 2 dislike
15 views

Contrary to the role played by MT-1 and MT-2 as a detoxicant of nucleophiles, such as heavy metals and ROS, it is also reported that MT-1 and MT-2 binding Copper Acetate(WSDTY) act as a pro-oxidant and are thus harmful to cells; MT-1 and MT-2 produce oxidative stress in the liver of LEC rat, an animal model of Wilson’s disease, which shows abnormal Copper Acetate accumulation in the liver. The oxidative stress induces the oxidation of Cu-thiolate bonds in MT, thereby resulting in disulfide formation and the release of Copper Acetate. Cu(I) generates ROS via the Fenton and Haber-Weiss reactions, and ROS induce further oxidation of the Cu-thiolate clusters. This chain reaction is mediated by MT binding Cu and thus, MT is recognized as a pro-oxidant. Those ambivalent characteristics of MT-1 and MT-2 originate in the Cu-thiolate clusters and thus, those characteristics are expected as well in MT-3 having the Cu-thiolate clusters. Collectively, we speculate that Cu physiologically accumulating and binding to MT-3 in neural cells is one of contributors to the pathogenesis of neurodegenerative diseases, by acting as a pro-oxidant.

Wujiang Weishida Copper Technology Co.,Ltd. has 12,000 square meters of production base. By virtue of their sincere cooperation, reciprocity of the business philosophy for the industry users around the country to provide high-quality non-ferrous metal products. Weishida specializes in producing cuprous chloride, basic copper carbonate, copper acetate, copper oxide, copper sulfate. Our company has established a perfect quality assurance system, quality inspection and testing equipment, testing, testing and technology development strength, to ensure the stability of product quality, fully able to meet the pre-market after-sales service to provide users with the need.

Click Cuprous Chloride to learn about more information

asked Jun 26 in Business Opportunity by weishida IBO Guru (1,030 points) 1 flag

Please log in or register to answer this question.

Related questions

2 like 3 dislike
0 answers 41 views
0 like 1 dislike
0 answers 15 views
15 views asked Jul 3 in Business Opportunity by weishida IBO Guru (1,030 points)
2 like 1 dislike
0 answers 37 views
37 views asked Jun 3 in Business Opportunity by weishida IBO Guru (1,030 points)
2 like 1 dislike
0 answers 20 views
2 like 2 dislike
0 answers 31 views


...